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HLY78
Cat. No.:
OB0225WX-1722
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
HLY78 is a small molecule activator of the Wnt/β-catenin signaling pathway that specifically targets the DIX domain of Axin, thereby strengthening the Axin-LRP6 binding interaction.
Synonym:
4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine; 854847-61-3; HLY78; 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine; CHEMBL223713; 4-ethyl-5-methyl-6H-[1,3]dioxolo[4,5-j]phenanthridine; 4-Ethyl-5-methyl-8,9-methylenedioxy-5,6-dihydrophenantridine; HLY-78; 4-ethyl-5-methyl-6H,9H-[1,3]dioxolo[4,5-j]phenanthridine; 4-ethyl-5-methyl-8,9-methylenedioxy-5,6-dihydrophenanthridine; 4-ethyl-5-methyl-5H,6H,9H-[1,3]dioxolo[4,5-j]phenanthridine
CAS No.:
854847-61-3
Compound CID:
44422459
Formula:
C17H17NO2
Formula Weight:
267.32
Specification
Relative Density:
1.208 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
HLY78 is applied in developmental biology as an activator of the Wnt/beta-catenin pathway to investigate its role in tissue regeneration and cell fate determination through binding to the Axin-DAX domain.
Library Information
Target:
Wnt/β-Catenin
Receptor:
Wnt/β-Catenin
Pathways:
Stem cells; Cytoskeletal signaling
Plate Number:
AOCL-23
Plate Location:
a7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 187.04 mM
