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Wnt agonist 1
Cat. No.:
OB0225WX-2731
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Wnt agonist 1 is a cell-permeable activator of the Wnt signaling pathway that induces beta-catenin- and TCF-dependent transcription with an EC50 of 0.7 micromolar.
Synonym:
BML-284 HCL; BML-284 hydrochloride; AMBMP hydrochloride; AMBMP HCL; 2095432-75-8; Wnt agonist 1; AMBMP hydrochloride; AMBMPHydrochloride; BML-284 (hydrochloride); BML-284 HCl; N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride; N4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine hydrochloride; 4-N-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine Hydrochloride; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine;hydrochloride; N4-(2H-1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine hydrochloride; N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine Hydrochloride; N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine Hydrochloride (1:1)
CAS No.:
2095432-75-8
Compound CID:
122705993
Formula:
C19H18N4O3·HCl
Formula Weight:
386.83
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Wnt agonist 1 is utilized in developmental and stem cell research as a cell-permeable small molecule to investigate the activation of the Wnt/beta-catenin signaling pathway and its impact on cellular differentiation.
Library Information
Target:
Wnt/β-Catenin
Pathways:
Stem cells & Wnt
Plate Number:
L6700-10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
77 mg/mL; 199.05 mM
ALogP:
3.837
HBA_Count:
5
HBD_Count:
2
Rotatable Bond:
5





