Products
Online Inquiry
WAY-262611
Cat. No.:
OB0225WX-1716
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
WAY262611 is a Wnt/β-catenin agonist that functions as a Dkk1 inhibitor, yielding an EC50 of 0.63 μM in TCF-luciferase reporter assays.
Synonym:
1123231-07-1; (1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine; [1-(4-naphthalen-2-ylpyrimidin-2-yl)piperidin-4-yl]methanamine; {1-[4-(naphthalen-2-yl)pyrimidin-2-yl]piperidin-4-yl}methanamine; WAY262611 2HCl; DKK1 inhibitor; WAY 262611; ({1-[4-(2-naphthyl)pyrimidin-2-yl]piperidin-4-yl}methyl)amine; [1-[4-(2-naphthalenyl)-2-pyrimidinyl]-4-piperidinyl]methanamine
CAS No.:
1123231-07-1
Compound CID:
25199517
Formula:
C20H22N4
Formula Weight:
318.42
Specification
Targets&IC50:
β-catenin (TCF-Luciferase assay): 0.63 μM
Relative Density:
1.169 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
WAY-262611 is employed in musculoskeletal research as a small molecule Dkk1 inhibitor to study the potentiation of Wnt signaling and its effects on bone density and mineralisation.
Library Information
Target:
Wnt/β-Catenin
Receptor:
β-Catenin
Pathways:
Stem cells; Cytoskeletal signaling
Plate Number:
AOCL-22
Plate Location:
h11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
42 mg/mL; 131.90 mM
