Orteronel

Cat. No.: OB0225WX-2400

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

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Product Overview

Description: Orteronel is a potent human 17,20-lyase inhibitor (IC50: 38 nM) that functions as an androgen biosynthesis blocker with 1000-fold selectivity over other CYP enzymes.

Synonym: TAK-700; 426219-18-3; 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide; TAK-700 (Orteronel); Orteronel (racemate); TAK700; Orteronel (racemic); 6-(7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl)-N-methylnaphthalene-2-carboxamide; TAK 700 racemate; (R)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide; 6-{7-hydroxy-5H,6H,7H-pyrrolo[1,2-c]imidazol-7-yl}-N-methylnaphthalene-2-carboxamide; Oteronel; 6-[7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthamide; TAK-700; Orteronel; TAK-700 (racemate); Orteronel (TAK-700)

CAS No.: 426219-18-3

Compound CID: 9883029

Formula: C₁₈H₁₇N₃O₂

Formula Weight: 307.35

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Orteronel is used in endocrine research as a selective inhibitor of 17,20-lyase (CYP17A1) to investigate the suppression of androgen biosynthesis in models of castration-resistant prostate cancer.