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ML351
Cat. No.:
OB0225WX-1831
Appearance:
Solid
Purity:
≥97%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
ML351 is a potent small molecule inhibitor of human 15-lipoxygenase-1 (15-LOX-1) featuring a half-maximal inhibitory concentration (IC50) of 200 nM.
Synonym:
847163-28-4; ML 351; 5-(methylamino)-2-(naphthalen-1-yl)-1,3-oxazole-4-carbonitrile; 5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile; MLS000082299; 5-(Methylamino)-2-(naphthalen-1-yl)oxazole-4-carbonitrile; 5-(methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile; 5-Methylamino-2-naphthalen-1-yl-oxazole-4-carbonitrile; 5-(methylamino)-2-(1-naphthyl)oxazole-4-carbonitrile; Z1213743771; 5-(methylamino)-2-(1-naphthyl)-1,3-oxazol-4-yl cyanide
CAS No.:
847163-28-4
Compound CID:
664510
Formula:
C15H11N3
Formula Weight:
249.27
Specification
Targets&IC50:
15-LOX: 200 nM
Relative Density:
1.29 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
ML351 is utilized in biochemical research as a potent and selective inhibitor of 15-lipoxygenase-1 (15-LOX-1) to study the role of eicosanoid signaling in ferroptosis and cardiovascular diseases.
Library Information
Target:
Lipoxygenase
Receptor:
15 LOX
Pathways:
Metabolism
Plate Number:
AOCL-24
Plate Location:
e2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
22.5 mg/mL; 90.26 mM
