AZ876

Cat. No.: OB0225WX-2655

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: AZ876 is a novel liver X receptor (LXR) agonist with high binding affinity, demonstrated by Ki values of 0.007 microM for hLXR-alpha and 0.011 microM for hLXR-beta.

Synonym: 898800-26-5; AZ 876; AZ12260493; AZ-12260493; 2-tert-Butyl-5-phenyl 4-[(4-piperidin-1-ylphenyl)amino]isothiazol-3(2H)-one 1,1-dioxide; AZ 12260493; AZ-876; 2-tert-butyl-1,1-dioxo-5-phenyl-4-(4-piperidin-1-ylanilino)-1,2-thiazol-3-one; 2-tert-butyl-1,1-dioxo-5-phenyl-4-[(4-piperidin-1-ylphenyl)amino]-1,2-thiazol-3-one; 2-(1,1-Dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-3(2H)-isothiazolone 1,1-dioxide; 2-(tert-Butyl)-5-phenyl-4-((4-(piperidin-1-yl)phenyl)amino)isothiazol-3(2H)-one 1,1-dioxide; 2-tert-butyl-1,1-dioxo-5-phenyl-4-((4-piperidin-1-ylphenyl)amino)-1,2-thiazol-3-one; 3(2H)-isothiazolone, 2-(1,1-dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-, 1,1-dioxide; 2-tert-Butyl-5-pheny 4-[(4-piperidin-1-ylphenyl)amino]isothiazol-3(2H)-one 1,1-dioxide

CAS No.: 898800-26-5

Compound CID: 11655079

Formula: C₂₄H₂₉N₃O₃S

Formula Weight: 439.57

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: AZ876 is utilized in cardiovascular and metabolic studies as a potent LXR agonist to investigate the enhancement of reverse cholesterol transport and the regulation of gene expression in atherosclerosis models.