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ML-298
Cat. No.:
OB0225WX-2100
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
ML-298 is a specific and potent inhibitor of phospholipase D2 (PLD2) characterized by an IC50 of 355 nM.
Synonym:
ML298; CID53393915; 1426916-02-0; ML298 free base; 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide; 3,4-Difluoro-N-(2-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro [4.5]decan-8-yl)ethyl)benzamide; 3,4-difluoro-N-(2-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamide; 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide; 3,4-bis(fluoranyl)-N-[2-[1-(3-fluorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid; 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide;2,2,2-trifluoroacetic acid; 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]benzamide;2,2,2-trifluoroacetic acid
CAS No.:
1426916-02-0
Compound CID:
53393916
Formula:
C22H23F3N4O2
Formula Weight:
432.44
Specification
Targets&IC50:
PLD2: 355 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
ML-298 is employed in cell signaling research as a potent and selective inhibitor of phospholipase D2 (PLD2) to investigate the regulation of membrane trafficking and cellular proliferation.
Library Information
Target:
Phospholipase
Receptor:
PLD2
Pathways:
Metabolism
Plate Number:
AOCL-27
Plate Location:
h4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
9 mg/mL; 20.81 mM





