Products
Online Inquiry
Febuxostat
Cat. No.:
OB0225WX-1589
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Febuxostat is a non-purine selective inhibitor characterized by its potent suppression of xanthine oxidase activity.
Synonym:
TMX 67;TEI 6720; 144060-53-7; Adenuric; Uloric; 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid; Feburic; TMX-67; Tei 6720; Tei-6720; TMX 67; 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid; Zurig; Donifoxate; Febuxostatum; Febuday; Goturic; Goutex; 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-; 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic acid; 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid; Febric; 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-1,3-thiazole-5-carboxylic acid; 2-(3-cyano-4-isobutyloxy)-phenyl-4-methyl-5-thiazolecarboxylic acid; 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid
CAS No.:
144060-53-7
Compound CID:
134018
Formula:
C16H16N2O3S
Formula Weight:
316.37
Specification
Targets&IC50:
XO: 0.6 nM(Ki)
Relative Density:
1.31 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Febuxostat is used in metabolic research as a potent, non-purine selective inhibitor of xanthine oxidase to explore the suppression of uric acid production in hyperuricemia models.
Library Information
Target:
Reactive oxygen species; XO
Receptor:
Reactive oxygen species; XO
Pathways:
Metabolism; Immunology/Inflammation
Plate Number:
AOCL-21
Plate Location:
d4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 158.04 mM
Ethanol Max Solubility:
15.8 mg/mL; 50 mM
ALogP:
3.468
HBA_Count:
3
HBD_Count:
0
Rotatable Bond:
5
