IWP-L6

Cat. No.: OB0225WX-2678

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: IWP-L6 is a high-potency small molecule that antagonizes the PORCN enzyme, featuring an EC50 of 0.5 nM.

Synonym: Porcn Inhibitor III; 1427782-89-5; IWP L6; 2-((4-Oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(5-phenylpyridin-2-yl)acetamide; 2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]-N-(5-phenylpyridin-2-yl)acetamide; 2-({4-oxo-3-phenyl-3H,4H,6H,7H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl)-N-(5-phenylpyridin-2-yl)acetamide; N-(5-phenyl-2-pyridinyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide; 2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)-N-(5-phenylpyridin-2-yl)acetamide; N-(5-Phenyl-2-pyridinyl)-2-[(3,4,6, 7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin- 2-yl)thio]acetamide

CAS No.: 1427782-89-5

Compound CID: 71601111

Formula: C₂₅H₂₀N₄O₂S₂

Formula Weight: 472.58

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: IWP-L6 is used in molecular biology as a highly potent and selective inhibitor of Porcn to investigate the regulation of Wnt protein palmitoylation and its impact on signal transduction.