GNF-6231

Cat. No.: OB0225WX-2773

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: GNF-6231 acts as a potent and orally bioavailable inhibitor of the porcupine (Porcn) enzyme, featuring a half-maximal inhibitory concentration (IC50) of 0.8 nM.

Synonym: 1243245-18-2; N-[5-(4-acetylpiperazin-1-yl)pyridin-2-yl]-2-[6-(2-fluoropyridin-4-yl)-5-methylpyridin-3-yl]acetamide; N-(5-(4-Acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-fluoro-3-methyl-[2,4'-bipyridin]-5-yl)acetamide; N-[5-(4-Acetyl-1-piperazinyl)-2-pyridinyl]-2'-fluoro-3-methyl[2,4'-bipyridine]-5-acetamide; N-[5-(4-acetylpiperazin-1-yl)pyridin-2-yl]-2-{2'-fluoro-3-methyl-[2,4'-bipyridin]-5-yl}acetamide; N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2''-fluoro-3-methyl-2,4''-bipyridin-5-yl)acetamide; N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-fluoro-3-methyl-2,4'-bipyridin-5-yl)acetamide

CAS No.: 1243245-18-2

Compound CID: 46927297

Formula: C₂₄H₂₅FN₆O₂

Formula Weight: 448.49

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: GNF-6231 is employed in developmental biology and oncology research as a potent Porcupine inhibitor to investigate the disruption of Wnt protein secretion and the suppression of Wnt-driven signaling in malignant models.