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Vitamin B12 test kit

Bisdemethoxycurcumin

Cat. No.: OB0225WX-1694
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and LC-MS.
Size:
Bisdemethoxycurcumin
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Product Overview

Description: Bisdemethoxycurcumin is a stable demethoxy derivative of curcumin that downregulates the p300 coactivator to suppress Wnt/β-catenin signaling and modulates macrophage phagocytosis via interaction with 1α, 25-dihydroxy vitamin D3.
Synonym: Curcumin III; Didemethoxycurcumin; 24939-16-0; (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione; Bis(4-hydroxycinnamoyl)methane; Bis-demethoxycurcumin; Bisdemethoxycucurmin; Bisdesmethoxycurcumin; (E,E)-Bisdemethoxycurcumin; Bis(p-hydroxycinnamoyl)methane; 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-; 1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione; 1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione; 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-; BHCMT; p,p'-Dihydroxydicinnamoylmethane; Curcumin III;Didemethoxycurcumin; Curcumin Lll; Curcuminoid A; Bisdemethoxy Curcumin; MFCD03419284; di-p-coumaroylmethane; Dide Methoxycurcu Min; BDMC;(E,E)-Curcumin III; INS NO.100(III); (1E,6E)-1,7-Bis(4-hydroxyphenyl)-hepta-1,6-diene-3,5-dione; 1,7-bis(4-hydroxyphenyl)-1,6-Heptadiene-3,5-dione(E,E); 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3,6-heptatrien-5-one; (1E,6E)-1,7-Bis-(4-hydroxy-phenyl)-hepta-1,6-diene-3,5-dione; 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (E,E)-; 5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one; (1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one
CAS No.: 24939-16-0
Compound CID: 5315472
Formula: C19H16O4
Formula Weight: 308.33

Specification

Relative Density: 1.285 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Bisdemethoxycurcumin is used in pharmacological research as a natural derivative to explore its capacity to modulate Wnt signaling and its impact on inflammatory and neoplastic pathways.

Library Information

Target: Epigenetic reader domain; Wnt/β-Catenin
Receptor: p300; Wnt/β-Catenin
Pathways: Stem cells; Chromatin/Epigenetic; Cytoskeletal signaling
Plate Number: AOCL-22
Plate Location: f9
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 10 mg/mL
Ethanol Max Solubility: 5 mg/mL
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