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Bisdemethoxycurcumin
Cat. No.:
OB0225WX-1694
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Bisdemethoxycurcumin is a stable demethoxy derivative of curcumin that downregulates the p300 coactivator to suppress Wnt/β-catenin signaling and modulates macrophage phagocytosis via interaction with 1α, 25-dihydroxy vitamin D3.
Synonym:
Curcumin III; Didemethoxycurcumin; 24939-16-0; (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione; Bis(4-hydroxycinnamoyl)methane; Bis-demethoxycurcumin; Bisdemethoxycucurmin; Bisdesmethoxycurcumin; (E,E)-Bisdemethoxycurcumin; Bis(p-hydroxycinnamoyl)methane; 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-; 1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione; 1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione; 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-; BHCMT; p,p'-Dihydroxydicinnamoylmethane; Curcumin III;Didemethoxycurcumin; Curcumin Lll; Curcuminoid A; Bisdemethoxy Curcumin; MFCD03419284; di-p-coumaroylmethane; Dide Methoxycurcu Min; BDMC;(E,E)-Curcumin III; INS NO.100(III); (1E,6E)-1,7-Bis(4-hydroxyphenyl)-hepta-1,6-diene-3,5-dione; 1,7-bis(4-hydroxyphenyl)-1,6-Heptadiene-3,5-dione(E,E); 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3,6-heptatrien-5-one; (1E,6E)-1,7-Bis-(4-hydroxy-phenyl)-hepta-1,6-diene-3,5-dione; 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (E,E)-; 5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one; (1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one
CAS No.:
24939-16-0
Compound CID:
5315472
Formula:
C19H16O4
Formula Weight:
308.33
Specification
Relative Density:
1.285 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Bisdemethoxycurcumin is used in pharmacological research as a natural derivative to explore its capacity to modulate Wnt signaling and its impact on inflammatory and neoplastic pathways.
Library Information
Target:
Epigenetic reader domain; Wnt/β-Catenin
Receptor:
p300; Wnt/β-Catenin
Pathways:
Stem cells; Chromatin/Epigenetic; Cytoskeletal signaling
Plate Number:
AOCL-22
Plate Location:
f9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
10 mg/mL
Ethanol Max Solubility:
5 mg/mL





