CP-640186

Cat. No.: OB0225WX-1679

Appearance: Solid

Purity: ≥98%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: CP-640186 acts as a pan-inhibitor of acetyl-CoA carboxylase (ACCase), demonstrating effective enzymatic suppression with IC50 values of 53 nM (ACC1) and 61 nM (ACC2) in rat models.

Synonym: CP-640,186; CP 640186; 591778-68-6; (3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4'-bipiperidine; [(3R)-1-[1-(anthracene-9-carbonyl)piperidin-4-yl]piperidin-3-yl]-morpholin-4-ylmethanone; (R)-anthracen-9-yl(3-(morpholine-4-carbonyl)-[1,4'-bipiperidin]-1'-yl)methanone; (Anthracen-9-yl)((3R)-3-((morpholin-4-yl)carbonyl)(1,4')bipiperidinyl-1'-yl)methanone; Methanone, ((3R)-1'-(9-anthracenylcarbonyl)(1,4'-bipiperidin)-3-yl)-4-morpholinyl-; Morpholine, 4-(((3R)-1'-(9-anthracenylcarbonyl)(1,4'-bipiperidin)-3-yl)carbonyl)-; (3R)-1'-(anthracen-9-ylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4'-bipiperidine; RCP; CP-640186 Hcl; {(3R)-1'-(anthracen-9-ylcarbonyl)[1,4'-bipiperidin]-3-yl}(morpholin-4-yl)methanone; MFCD25976696; (3R)-1''-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4''-bipiperidine; (3R)-1''-(anthracen-9-ylcarbonyl)-3-(morpholin-4-ylcarbonyl)-1,4''-bipiperidine; (3R)-Anthracen-9-yl-[3-(morpholine-4-carbonyl)-[1,4']bipiperidinyl-1'-yl]-methanone; {(3R)-1''-(anthracen-9-ylcarbonyl)[1,4''-bipiperidin]-3-yl}(morpholin-4-yl)methanone

CAS No.: 591778-68-6

Compound CID: 449097

Formula: C₃₀H₃₅N₃O₃

Formula Weight: 485.62

Specification

Targets&IC50: ACC12: 61 nM; ACC1: 53 nM

Relative Density: 1.245 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: CP-640186 is utilized as a biochemical probe in metabolic experiments to investigate the impact of blocking malonyl-CoA production on energy expenditure and insulin sensitivity.