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JNJ-42226314
Cat. No.:
OB0225WX-1881
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
JNJ-42226314 is a highly selective, non-covalent inhibitor of monoacylglycerol lipase (MAGL) that modulates levels of the endogenous cannabinoid 2-acryloylglycerol (2-AG).
Synonym:
1252765-13-1; [1-(4-fluorophenyl)indol-5-yl]-[3-[4-(1,3-thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone; SCHEMBL698521; 1-(4-Fluorophenyl)-5-({3-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]azetidin-1-yl}carbonyl)-1H-indole
CAS No.:
1252765-13-1
Compound CID:
59625954
Formula:
C26H24FN5O2S
Formula Weight:
489.56
Specification
Relative Density:
1.44 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
JNJ-42226314 is employed in pharmacological research as an orally bioavailable and selective MAGL inhibitor to study the therapeutic potential of endocannabinoid modulation in stress-related models.
Library Information
Target:
Lipase
Receptor:
MAGL
Pathways:
Metabolism
Plate Number:
AOCL-25
Plate Location:
b2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 204.26 mM
