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KD-026
Cat. No.:
0225LY-1242
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by LC-MS.
Size:
Add to basket
Product Overview
Description:
KD-026 is a microsomal triglyceride transfer protein (MTP) inhibitor (IC50: 8.0 nM) currently utilized in studies related to type 2 diabetes.
Synonym:
SLx 4090; SLx4090;KD026; SLx-4090; 913541-47-6; KD-026; 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-6-[[[6-methoxy-4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-, phenyl ester; Phenyl 6-[[3-methoxy-2-[4-(trifluoromethyl)phenyl]benzoyl]amino]-3,4-dihydro-1H-isoquinoline-2-carboxylate; 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-6-(((6-methoxy-4'-(trifluoromethyl)(1,1'-biphenyl)-2-yl)carbonyl)amino)-, phenyl ester; Phenyl 6-((3-methoxy-2-(4-(trifluoromethyl)phenyl)benzoyl)amino)-3,4-dihydro-1H-isoquinoline-2-carboxylate; Phenyl 6-(6-methoxy-4'-(trifluoromethyl)-(1,1'-biphenyl)-2-amido)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
CAS No.:
913541-47-6
Compound CID:
53497429
Formula:
C31H25F3N2O4
Formula Weight:
546.54
Specification
Targets&IC50:
ApoB: 9.6 nM; MTP: 8.0 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
KD-026 can be used in lipid signaling research to investigate the specific inhibition of triglyceride-related metabolic pathways.
Library Information
Target:
MTP
Receptor:
MTTP
Pathways:
Metabolism
Plate Number:
AOCL-16
Plate Location:
h9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 100.63 mM
