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Marein
Cat. No.:
0225LY-1023
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Marein protects PC12 cells from methylglyoxal-induced damage by activating the AMPK pathway and preserving mitochondrial function, suggesting potential for treating diabetic encephalopathy.
Synonym:
535-96-6; Okanin-4'-O-glucoside; (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one; CY787E65J4; 2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl)-, (E)-; (E)-3-(3,4-Dihydroxyphenyl)-1-(4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl)-2-propen-1-one; Marein with hplc; (E)-3-(3,4-dihydroxyphenyl)-1-(2,3-dihydroxy-4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyphenyl)prop-2-en-1-one; (E)-3-(3,4-dihydroxyphenyl)-1-(2,3-dihydroxy-4-(3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyphenyl)prop-2-en-1-one; (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one
CAS No.:
535-96-6
Compound CID:
6441269
Formula:
C21H22O11
Formula Weight:
450.39
Specification
Targets&IC50:
HDAC: 100 µM (IC50)
Relative Density:
1.664 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Marein can be used in antioxidant research to explore its role in protecting cells from high glucose-induced oxidative stress.
Library Information
Target:
HDAC; AMPK; Glucose transporter
Receptor:
Akt; AMPK; GLUT; HDAC
Pathways:
Metabolism; Chromatin/Epigenetic; Cytoskeletal signaling; DNA damage/DNA repair; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-14
Plate Location:
b6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
60 mg/mL; 133.22 mM





