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TOFA
Cat. No.:
OB0225WX-1677
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
TOFA is an allosteric chemical modulator that specifically targets the alpha subunit of acetyl-CoA carboxylase (ACCA).
Synonym:
MDL14514; RMI14514; 54857-86-2; 5-(Tetradecyloxy)-2-furoic acid; Olumacostat; 5-tetradecoxyfuran-2-carboxylic acid; 5-Tetradecyloxy-2-furonic acid; RMI-14514; 5-(Tetradecyloxy)-2-furancarboxylic acid; 2-Furancarboxylic acid, 5-(tetradecyloxy)-; 5-(tetradecyloxy)furan-2-carboxylic acid; RMI 14,514; TOFA (5-(Tetradecyloxy)-2-furoic acid); 5-tetradecyloxy-2-furoic acid
CAS No.:
54857-86-2
Compound CID:
115175
Formula:
C19H32O4
Formula Weight:
324.45
Specification
Relative Density:
1.003 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
TOFA is applied in lipid metabolism research as an allosteric inhibitor of ACC to study the molecular mechanisms of fatty acid synthesis and its role in cellular lipid accumulation.
Library Information
Target:
ACC
Receptor:
ACCA
Pathways:
Metabolism
Plate Number:
AOCL-22
Plate Location:
e2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
6.88 mg/mL; 21.19 mM
