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Setileuton
Cat. No.:
OB0225WX-1861
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
Setileuton is a specific and potent inhibitor of the 5-LOX enzyme characterized by its high target affinity.
Synonym:
MK0633; MK 0633; MK-0633; 910656-27-8; 4-(4-Fluorophenyl)-7-[[[5-[(1S)-1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl]amino]methyl]-2H-1-benzopyran-2-one; 4-(4-fluorophenyl)-7-[[[5-[(2S)-1,1,1-trifluoro-2-hydroxybutan-2-yl]-1,3,4-oxadiazol-2-yl]amino]methyl]chromen-2-one; (S)-4-(4-fluorophenyl)-7-(((5-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1,3,4-oxadiazol-2-yl)amino)methyl)-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 4-(4-fluorophenyl)-7-(((5-((1S)-1-hydroxy-1-(trifluoromethyl)propyl)-1,3,4-oxadiazol-2-yl)amino)methyl)-; 4-(4-fluorophenyl)-7-(((5-(1-hydroxy-1-(trifluoromethyl)propyl)-1,3,4-oxadiazol-2-yl)amino)methyl)-2H-1-benzopyran-2-one; 4-(4-fluorophenyl)-7-(((5-((1S)-1-hydroxy-1-(trifluoromethyl)propyl)-1,3,4-oxadiazol-2-yl)amino)methyl)-2H-1-benzopyran-2-one; MK0633; MK 0633
CAS No.:
910656-27-8
Compound CID:
11856170
Formula:
C22H17F4N3O4
Formula Weight:
463.38
Specification
Relative Density:
1.478 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Setileuton is utilized in respiratory and cardiovascular research as a 5-lipoxygenase inhibitor to investigate the suppression of leukotriene synthesis in asthma and atherosclerosis studies.
Library Information
Target:
Lipoxygenase
Receptor:
5-LOX
Pathways:
Metabolism
Plate Number:
AOCL-24
Plate Location:
h2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
2mM DMSO
DMSO Max Solubility:
4.63 mg/mL; 10 mM
