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ThioLox
Cat. No.:
OB0225WX-1840
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
ThioLox is a competitive inhibitor of 15-lipoxygenase-1 (15-LOX-1) with an IC50 of 12 μM, possessing significant molecular properties that protect against glutamate-induced toxicity.
Synonym:
1202193-89-2; ThioLox-ThiopheneA9; 2-amino-N-butyl-5-phenylthiophene-3-carboxamide; 2-amino-N-butyl-5-phenyl-thiophene-3-carboxamide
CAS No.:
1202193-89-2
Compound CID:
53383638
Formula:
C15H18N2OS
Formula Weight:
274.38
Specification
Targets&IC50:
15-LOX1: 3.3 (Ki)
Relative Density:
1.160 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
ThioLox is applied in biochemical studies as a specialized sulfur-containing lipoxygenase inhibitor to investigate the mechanistic details of enzyme-inhibitor interactions and the control of redox signaling.
Library Information
Target:
Lipoxygenase
Receptor:
15 LOX
Pathways:
Metabolism
Plate Number:
AOCL-24
Plate Location:
e11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
90.0 mg/mL; 328.0 mM
