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Halobetasol propionate
Cat. No.:
OB0225WX-2095
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Halobetasol propionate is a synthetic corticosteroid that induces phospholipase A2 inhibitory proteins, thereby blocking the release of arachidonic acid and the subsequent biosynthesis of leukotrienes and prostaglandins.
Synonym:
Ulobetasol propionate; BMY-30056; CGP-14458; 66852-54-8; Ultravate; Miracorten; Halobetasol (propionate); Jemdel; BMY-30056; 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate; Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6alpha,11beta,16beta)-; [(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate; MFCD00866013; 6-fluoroclobetasol 17-propionate; (6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
CAS No.:
66852-54-8
Compound CID:
6918178
Formula:
C25H31ClF2O5
Formula Weight:
484.96
Specification
Relative Density:
1.31 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Halobetasol propionate is used in dermatological research as a high-potency corticosteroid to investigate the suppression of inflammatory mediators and the modulation of immune responses in skin disease models.
Library Information
Target:
Phospholipase
Receptor:
PLA2
Pathways:
Metabolism
Plate Number:
AOCL-27
Plate Location:
g8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
90 mg/mL; 185.6 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
36 mg/mL; 74.2 mM
ALogP:
3.797
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
5
