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NG-497
Cat. No.:
OB0225WX-1883
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
NG-497 is a selective small molecule that targets the enzymatically active patatin-like domain of human adipose triglyceride lipase (ATGL), binding to a hydrophobic lumen to reversibly inhibit lipolysis.
Synonym:
NG497; 2598242-66-9
CAS No.:
2598242-66-9
Compound CID:
155594277
Formula:
C18H21NO4
Formula Weight:
315.36
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
NG-497 is utilized in metabolic research as a potent inhibitor of hormone-sensitive lipase (HSL) to investigate the blockage of fatty acid release from adipocytes and its effect on insulin sensitivity.
Library Information
Target:
Lipase
Receptor:
ATGL
Pathways:
Metabolism
Plate Number:
AOCL-25
Plate Location:
b4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 158.55 mM
