Obeticholic Acid

Cat. No.: OB0225WX-2696

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Obeticholic Acid is a potent, selective agonist of the farnesoid X receptor (FXR) with an EC50 of 99 nM and is known to modulate cellular autophagy.

Synonym: INT-747; 6-ECDCA; 6-Ethylchenodeoxycholic acid; 459789-99-2; Ocaliva; Obetichloic acid; INT747; 6alpha-Ethyl-chenodeoxycholic acid; 6alpha-ethylchenodeoxycholic acid; 6-alpha-ethylchenodeoxycholic acid; (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid; 6alpha-ethyl-3alpha,7alpha-dihydroxy-5beta-cholan-24-oic acid; (4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethyl-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid; Obeticholic acid [USAN]; 6-ethyl chenodeoxycholic acid; 3alpha,7alpha-dihydroxy-6alpha-ethyl-5beta-cholan-24-oic acid; (3alpha,5beta,6alpha,7alpha,8xi)-6-Ethyl-3,7-dihydroxycholan-24-oic acid; (3beta,5beta,6alpha,7beta)-6-ethyl-3,7-dihydroxycholan-24-oic acid

CAS No.: 459789-99-2

Compound CID: 447715

Formula: C₂₆H₄₄O₄

Formula Weight: 420.63

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Obeticholic Acid is used in hepatology research as a potent and selective FXR agonist to investigate the regulation of bile acid transport, hepatic lipid metabolism, and the modulation of fibrotic progression.