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Tacrolimus
Cat. No.:
OB0225LY-0421
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
Tacrolimus is an immunosuppressant widely used in research to probe the mechanisms of the immune response.
Synonym:
Fujimycin; FK506; FR900506; 104987-11-3; Tacrolimus anhydrous; Protopic; (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-Dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
CAS No.:
104987-11-3
Compound CID:
445643
Formula:
C44H69NO12
Formula Weight:
804.02
Specification
Relative Density:
1.19 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Tacrolimus can be used in immunology research or play an important role in organ transplantation research.
Library Information
Targets:
Serine/Threonine phosphatases; Immunophilins
Receptors:
FKBP-12; Phosphatase
Pathways:
Metabolism; Microbiology/Virology; Autophagy; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-6
Plate Location:
d7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
45 mg/mL; 55.97 mM
Ethanol Max Solubility:
80.4 mg/mL; 100 mM
Solubility:
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 8.04 mg/mL (10 mM)
ALogP:
4.832
HBA_Count:
9
HBD_Count:
2
Rotatable Bond:
7
