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MSDC-0602K
Cat. No.:
0225LY-0896
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, IC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
MSDC-0602K is a PPARγ-sparing thiazolidinedione (Ps-TZD) that binds to PPARγ with an IC50 of 18.25 μM and modulates the mitochondrial pyruvate carrier (MPC); it functions as an insulin sensitizer and is studied for its ability to improve fatty liver disease and insulin resistance.
Synonym:
Azemiglitazone potassium; 1314533-27-1; MSDC-0602 potassium; 2,4-Thiazolidinedione, 5-((4-(2-(3-methoxyphenyl)-2-oxoethoxy)phenyl)methyl)-, potassium salt (1:1)
CAS No.:
1314533-27-1
Compound CID:
87355566
Formula:
C19H16KNO5S
Formula Weight:
409.5
Specification
Targets&IC50:
PPARγ: 18.25 μM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
MSDC-0602K can be used in NASH research to evaluate its role as a mitochondrial pyruvate carrier inhibitor with PPAR gamma-sparing properties.
Library Information
Target:
PPAR
Receptor:
PPARγ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-12
Plate Location:
e5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 122.1 mM
