ML355

Cat. No.: OB0225WX-1851

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: ML355 is a highly selective and effective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, noted for its favorable ADME (absorption, distribution, metabolism, and excretion) profile.

Synonym: 1532593-30-8; ML355 free base; VLX-1005; ML-355; N-(1,3-benzothiazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamide; ML 355; N-(benzo[d]thiazol-2-yl)-4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide; Benzenesulfonamide, N-2-benzothiazolyl-4-(((2-hydroxy-3-methoxyphenyl)methyl)amino)-; N-(1,3-benzothiazol-2-yl)-4-{[(2-hydroxy-3-methoxyphenyl)methyl]amino}benzene-1-sulfonamide; N-2-Benzothiazolyl-4-(((2-hydroxy-3-methoxyphenyl)methyl)amino)benzenesulfonamide; N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-benzenesulfonamide; N-(1,3-benzothiazol-2-yl)-4-((2-hydroxy-3-methoxyphenyl)methylamino)benzenesulfonamide; N-Benzothiazol-2-yl-4-(2-hydroxy-3-methoxy-benzylamino)-bezenesulfonamide; N-(1,3-benzothiazol-2-yl)-4-[(2-hydroxy-3-methoxybenzyl)amino]benzenesulfonamide; N-(1,3-benzothiazol-2-yl)-4-{[(2-hydroxy-3-methoxyphenyl)methyl]amino}benzenesulfonamide; N-(Benzo[d]thiazol-2-yl)-4-(2-hydroxy-3-methoxybenzylamino)benzenesulfonamide; ML-355; ML-355;N-(Benzo[d]thiazol-2-yl)-4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide

CAS No.: 1532593-30-8

Compound CID: 70701426

Formula: C₂₁H₁₉N₃O₄S₂

Formula Weight: 441.52

Specification

Targets&IC50: 12-LOX: 0.34 μM

Relative Density: 1.481 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: ML355 is employed in hematology and vascular research as a first-in-class, selective 12-lipoxygenase inhibitor to investigate platelet activation and the prevention of thrombosis.