GW4064

Cat. No.: OB0225WX-2517

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

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Product Overview

Description: GW4064 is a selective farnesoid X receptor (FXR) agonist with an EC50 of 65 nM that stimulates autophagy while remaining inactive against other nuclear receptors at concentrations up to 1 micromolar.

Synonym: 278779-30-9; GW 4064; GW4064; GW-4064; (E)-3-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid; GW-4064X; MFCD09971006; 3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid; 3-[2-[2-Chloro-4-[[3-(2,6-Dichlorophenyl)-5-(1-Methylethyl)-4-Isoxazolyl]Methoxy]Phenyl]Ethenyl]Benzoic Acid; 3-[2-[2-Chloro-4-[[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-benzoic Acid; Benzoic acid, 3-(2-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl)methoxy)phenyl)ethenyl)-; (E)-GW 4064; 3-[(E)-2-(2-Chloro-4-{[3-(2,6-Dichlorophenyl)-5-(1-Methylethyl)isoxazol-4-Yl]methoxy}phenyl)ethenyl]benzoic Acid; 3-[2-[2-chloro-4-[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-ylmethoxy]phenyl]vinyl]benzoic acid; 3-(2-Chloro-4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid

CAS No.: 278779-30-9

Compound CID: 9893571

Formula: C₂₈H₂₂Cl₃NO₄

Formula Weight: 542.84

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: GW4064 is utilized in biochemical research as a non-steroidal FXR agonist to study the transcriptional regulation of lipid and glucose metabolism and the modulation of hepatic transport proteins.