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Saroglitazar
Cat. No.:
0225LY-0839
Appearance:
Oil
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
Saroglitazar is a PPAR agonist with high potency, featuring EC50 values of 0.65 pM for PPAR-alpha and 3 nM for PPAR-gamma.
Synonym:
Lipaglyn; 495399-09-2; (S)-2-Ethoxy-3-(4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethoxy)phenyl)propanoic acid; ZYH1; Saroglitazarum; (2S)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoic acid; (2S)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylsulfanyl)phenyl)-1H-pyrrol-1-yl(ethoxy)phenyl)propanoic acid; (2S)-2-ethoxy-3-[4-(2-{2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl}ethoxy)phenyl]propanoic acid; (2S)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylsulfanyl)phenyl)-1H-pyrrol-1-yl(ethoxy)phenyl)propanoic acid magnesium salt (2:1); Alpha-ethoxy-4-(2-(2-methyl-5-(4-methylthio)phenyl))-1H-pyrrol-1-yl)ethoxy))benzenepropanoic acid magnesium salt
CAS No.:
495399-09-2
Compound CID:
60151560
Formula:
C25H29NO4S
Formula Weight:
439.57
Specification
Targets&IC50:
PPARα: 0.65 pM （EC50; HepG2 cell）; PPARγ: 3 nM （EC50; HepG2 cell）
Relative Density:
1.15 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Saroglitazar can be used in diabetes research to investigate the unique dual modulation of PPAR alpha and gamma for glycemic control.
Library Information
Target:
PPAR
Receptor:
PPARα; PPARγ
Pathways:
Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-11
Plate Location:
g8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
22.5 mg/mL; 51.19 mM
