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Doxercalciferol
Cat. No.:
OB0225WX-2417
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Doxercalciferol is a synthetic analog of vitamin D2 that modulates parathyroid function by suppressing hormone synthesis and secretion.
Synonym:
1α-hydroxyvitamin D2; 54573-75-0; Hectorol; 1-Hydroxyergocalciferol; 1alpha-Hydroxyergocalciferol; 1alpha-hydroxyvitamin D2; 1-alpha-Hydroxyvitamin D2; TSA 840; 1-alpha-hydroxyergocalciferol; 1-Hydroxyvitamin D2; Doxercalciferolum; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol; (1S,3R,5Z,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraene-1,3-diol; MFCD00871065; 1.alpha.-Hydroxyvitamin D2; GZ427397; 1-.alpha.-hydroxyergocalciferol; (5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1alpha,3beta-diol; 1a-Hydroxy Vitamin D2; 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol, (1-alpha,3-beta,5Z,7E,22E)-; (5Z,7E,22E)-(1S,3R)-9,10-seco-5,7,10(19),22-ergostatetraene-1,3-diol; 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol, (1alpha,3beta,5Z,7E,22E)-; (1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R,E)-5,6-Dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
CAS No.:
54573-75-0
Compound CID:
5281107
Formula:
C28H44O2
Formula Weight:
412.65
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Doxercalciferol is employed in nephrology research as a synthetic vitamin D2 analog to investigate the suppression of parathyroid hormone (PTH) levels and the regulation of calcium metabolism in secondary hyperparathyroidism.
Library Information
Target:
VDR
Receptor:
VDR
Pathways:
Metabolism
Plate Number:
L6700-02
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
83 mg/mL; 201.14 mM
Ethanol Max Solubility:
70 mg/mL
ALogP:
6.337
HBA_Count:
0
HBD_Count:
2
Rotatable Bond:
5





