Lonidamine (AF-1890)

Cat. No.: OB0225WX-2501

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Lonidamine (AF-1890) is an orally active small molecule that functions as an inactivator of the enzyme hexokinase.

Synonym: Diclondazolic Acid, DICA; 50264-69-2; 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid; Diclondazolic acid; Doridamina; Lonidamina; Lonidaminum; Lonidamin; AF 1890; 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid; 1-(2,4-Dichlorbenzyl)-indazole-3-carboxylic acid; 1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid; 1-(2,4-dichlorobenzyl)indazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 1-(2,4-dichlorobenzyl)-; 1-(2,4-dichlorophenyl)-1h-indazol-3-carboxylic acid; Dichlondazolic acid; 1-((2,4-dichlorophenyl)methyl)indazole-3-carboxylic acid; 1-[(2,4-dichlorophenyl)methyl]-3-indazolecarboxylic acid

CAS No.: 50264-69-2

Compound CID: 39562

Formula: C₁₅H₁₀Cl₂N₂O₂

Formula Weight: 321.16

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Lonidamine (AF-1890) is utilized in metabolic oncology research as an inhibitor of hexokinase II to investigate the disruption of aerobic glycolysis and the induction of mitochondrial-mediated apoptosis in cancer cells.