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(-)-Hydroxycitric acid lactone
Cat. No.:
OB0225WX-2133
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
(-)-Hydroxycitric acid lactone is a potent inhibitor of ATP citrate lyase, the enzyme responsible for the extramitochondrial conversion of citrate into acetyl-CoA and oxaloacetate.
Synonym:
Garcinia lactone; 27750-13-6; (-)-Hydroxycitric acid lactone; Hydroxycitric acid lactone; (+)-Garcinia acid; D-Erythro-pentaric acid, 3-c-carboxy-2-deoxy-, 1,4-lactone; (2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylic acid; Hydroxycitric acid lactone,(-)-(p); 3-C-Carboxy-2-deoxy-d-erythro-pentaric acid 1,4-lactone; (2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylicacid; (2S,3S)-3-hydroxy-5-oxo-2,3,4,5-tetrahydrofuran-2,3-dicarboxylic acid
CAS No.:
27750-13-6
Compound CID:
9991606
Formula:
C6H6O7
Formula Weight:
190.11
Specification
Relative Density:
1.976 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
(-)-Hydroxycitric acid lactone is utilized in metabolic research as a derivative of hydroxycitric acid to investigate the inhibition of ATP-citrate lyase and its impact on fatty acid and cholesterol synthesis.
Library Information
Target:
ATP citrate lyase
Receptor:
ATP citrate lyase
Pathways:
Metabolism
Plate Number:
AOCL-28
Plate Location:
c8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
60 mg/mL; 315.61 mM
