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Hematein
Cat. No.:
OB0225WX-1656
Purity:
≥95%
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
Hematein is an allosteric Casein kinase II inhibitor (IC50: 0.74 μM) and an oxidation product of hematoxylin that suppresses the Wnt/TCF pathway and Akt/PKB Ser129 phosphorylation.
Synonym:
Hydroxybrasilein; 475-25-2; Haematein; Hematine; 3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one; Benz[b]indeno[1,2-d]pyran-9(6H)-one, 6a,7-dihydro-3,4,6a,10-tetrahydroxy-; 6a,7-Dihydro-3,4,6a,10-tetrahydroxybenz(b)indeno(1,2-d)pyran-9(6H)-one; Benz(b)indeno(1,2-d)pyran-9(6H)-one, 6a,7-dihydro-3,4,6a,10-tetrahydroxy-; 3,4,6a,10-tetrahydroxy-6a,7-dihydroindeno[2,1-c]chromen-9(6H)-one; MFCD00036187; 4,6a,9,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-3-one; 3,4,6a,10-Tetrahydroxy-6a,7-dihydrobenz(b)indeno(1,2-d)pyran-9(6H)-one; Benz[b]indeno[1, 6a,7-dihydro-3,4,6a,10-tetrahydroxy-; 3,4,6a,10-tetrahydroxy-6a,7-dihydrobenzo[b]indeno[1,2-d]pyran-9(6H)-one
CAS No.:
475-25-2
Compound CID:
135403802
Formula:
C16H12O6
Formula Weight:
300.26
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Hematein is used in biochemical research as a natural compound to investigate the inhibition of protein kinases and its potential role in regulating redox-sensitive signaling pathways.
Library Information
Target:
Akt; Wnt/β-Catenin
Receptor:
Akt; Wnt; CKII
Pathways:
Stem cells; PI3K/Akt/mTOR signaling; Cytoskeletal signaling
Plate Number:
AOCL-22
Plate Location:
b11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO





