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Epoxyazadiradione
Cat. No.:
OB0626WX-79
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Epoxyazadiradione is a natural neem-derived limonoid isolated from Azadirachta indica that exhibits versatile biochemical profiles, functioning as an inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity with established IC50 values of 6.4, 9.5, and 9.8 µM for human, Plasmodium falciparum, and Plasmodium yoelii enzymes, respectively.
Synonyms:
(5α,7α,13α,14β,15β,17α)-7-(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-24-norchola-1,20,22-triene-3,16-dione; 18385-59-6; Nimbinin; 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, 24-norchola-1,20,22-triene-3,16-dione deriv.; Azadiradione 14ss,15ss-Epoxide; 58525-91-0
CAS No.:
18385-59-6
Compound CID:
49863985
Formula:
C28H34O6
Formula Weight:
466.6
Specification
Source:
Synthetic
Solubility in Other Solvents:
Acetonitrile: 0.1-1 mg/mL; Chloroform: 0.1-1 mg/mL
Storage:
Storage at -20°C.
Applications:
Epoxyazadiradione serves as a limonoid natural product reference compound for structural characterization and investigation of specialized metabolite profiles. It supports analytical identification workflows, natural product chemistry studies, and comparative evaluation of structurally diverse small molecules.