Products
Online Inquiry
Cytochalasin H
Cat. No.:
OB0626WX-2429
Appearance:
Lyophilized solid
Purity:
≥95%
Identity:
Confirmed by HPLC.
Size:
Add to basket
Product Overview
Description:
Cytochalasin H is a potent fungal macrocyclic lactone that restricts cytoskeleton assembly by blocking the incorporation of actin monomers into growing filaments. This highly active cell-permeable molecule accelerates filament shortening dynamics, downregulates the production of reactive oxygen species in stimulated neutrophils, disrupts CD59 receptor endocytosis, and displays prominent anti-angiogenic properties.
Synonyms:
(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-1H-cycloundec[d]isoindol-1-one; 17-Deoxo-21-acetylzygosporin D; Paspalin P1; 3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1-oxo-1H,2H,3H,4H,5H,6H,6aH,9H,10H,11H,12H,15H,15bH-cycloundeca(e)isoindol-15-yl acetate; Cytochalasin O; Kodocytochalasin 1; (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; 53760-19-3
CAS No.:
53760-19-3
Compound CID:
13892272
Formula:
C30H39NO5
Formula Weight:
493.6
Specification
Source:
Phomopsis sp.
Solubility in DMSO:
Soluble
Solubility in Ethanol:
Soluble
Solubility in DMF:
Soluble
Solubility in Other Solvents:
Soluble in methanol.
Storage:
Storage at -20°C.
Applications:
Cytochalasin H serves as a research tool for investigations of actin cytoskeleton dynamics and cellular processes. It supports mechanistic studies of cytoskeletal organization, cell morphology, migration, and assay development in cell biology research.