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A-69412
Cat. No.:
OB0225WX-1846
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
A-69412 is a reversible and specific chemical inhibitor designed to target hydrophilic 5-lipoxygenase.
Synonym:
N-1-(Fur-3-ylethyl)-N-hydroxyurea; 123606-23-5; 1-[1-(furan-3-yl)ethyl]-1-hydroxyurea; N-1-(Fur-3-ylethyl)-N-hydroxyurea; Urea, N-[1-(3-furanyl)ethyl]-N-hydroxy-; A 69412; N-[1-(3-furyl)ethyl]-N-hydroxyurea; Urea, N-(1-(3-furanyl)ethyl)-N-hydroxy-; 1-(1-(furan-3-yl)ethyl)-1-hydroxyurea; N-[1-(Furan-3-yl)ethyl]-N-hydroxycarbamimidic acid
CAS No.:
123606-23-5
Compound CID:
130007
Formula:
C7H10N2O3
Formula Weight:
170.17
Specification
Targets&IC50:
5-LOX: 1 μM; LTB4: 1 μM
Relative Density:
1.33 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
A-69412 is applied in respiratory research as an orally active 5-lipoxygenase inhibitor to examine the suppression of leukotriene-mediated airway constriction and inflammation.
Library Information
Target:
Lipoxygenase
Receptor:
5-Lipoxygenase
Pathways:
Metabolism
Plate Number:
AOCL-24
Plate Location:
f7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
45 mg/mL; 264.44 mM
