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Vitamin B12 test kit

Torcetrapib

Cat. No.: 0225LY-1239
Purity: ≥99%
Identity: Confirmed by NMR, and LC-MS.
Size:
Torcetrapib
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Product Overview

Description: Torcetrapib is a CETP inhibitor designed to modulate cholesterol transfer between HDL and LDL, though it failed in clinical trials due to safety concerns.
Synonym: CP-529414; 262352-17-0; Torcetrapib; CP 529414; CP-529,414; (2R,4S)-4-((3,5-Bis-trifluoromethylbenzyl)methoxycarbonylamino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester; 1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-; ethyl (2R,4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboxylate; Ethyl (2R,4S)-4-((3,5-bis(trifluoromethyl)benzyl)(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate
CAS No.: 262352-17-0
Compound CID: 159325
Formula: C26H25F9N2O4
Formula Weight: 600.47

Specification

Targets&IC50: CETP: 37 nM
Relative Density: 1.42 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Torcetrapib can be used in biochemical studies to investigate the impact of CETP inhibition on cholesterol transport and vascular health.

Library Information

Target: CETP
Receptor: CETP
Pathways: Metabolism
Plate Number: AOCL-16
Plate Location: h6
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 30 mg/mL; 49.96 mM
ALogP: 7.345
HBA_Count: 4
HBD_Count: 0
Rotatable Bond: 10
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