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Torcetrapib
Cat. No.:
0225LY-1239
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Torcetrapib is a CETP inhibitor designed to modulate cholesterol transfer between HDL and LDL, though it failed in clinical trials due to safety concerns.
Synonym:
CP-529414; 262352-17-0; Torcetrapib; CP 529414; CP-529,414; (2R,4S)-4-((3,5-Bis-trifluoromethylbenzyl)methoxycarbonylamino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester; 1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-; ethyl (2R,4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboxylate; Ethyl (2R,4S)-4-((3,5-bis(trifluoromethyl)benzyl)(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate
CAS No.:
262352-17-0
Compound CID:
159325
Formula:
C26H25F9N2O4
Formula Weight:
600.47
Specification
Targets&IC50:
CETP: 37 nM
Relative Density:
1.42 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Torcetrapib can be used in biochemical studies to investigate the impact of CETP inhibition on cholesterol transport and vascular health.
Library Information
Target:
CETP
Receptor:
CETP
Pathways:
Metabolism
Plate Number:
AOCL-16
Plate Location:
h6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
30 mg/mL; 49.96 mM
ALogP:
7.345
HBA_Count:
4
HBD_Count:
0
Rotatable Bond:
10





