Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
FTI-277 hydrochloride
Cat. No.:
OB0225LY-0075
Appearance:
Viscous
Purity:
≥97%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Product Overview
Description:
FTI-277 hydrochloride is a small molecule inhibitor that is primarily used to inhibit the activity of the small GTPase farnesyltransferase, thereby affecting cellular signaling processes.
Synonym:
FTI 277 HCl; 180977-34-8; FTI-277 (hydrochloride); (S)-Methyl 2-(5-(((R)-2-amino-3-mercaptopropyl)amino)-[1,1'-biphenyl]-2-ylcarboxamido)-4-(methylthio)butanoate hydrochloride; Methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate; hydrochloride; (S)-Methyl2-(5-(((R)-2-amino-3-mercaptopropyl)amino)-[1,1'-biphenyl]-2-ylcarboxamido)-4-(methylthio)butanoatehydrochloride; Methyl (2S)-2-[(4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-phenylphenyl)formamido]-4-(methylsulfanyl)butanoate hydrochloride
CAS No.:
180977-34-8
Compound CID:
88309922
Formula:
C22H30ClN3O3S2
Formula Weight:
484.07
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
FTI-277 hydrochloride can be used for drug development and inhibitor selection.
Library Information
Targets:
GTPase superfamily; Transferase
Receptors:
Farnesyl Transferase; GGTase I; Ras
Pathways:
Metabolism; Apoptosis; MAPK; GPCR/G protein
Plate Number:
AOCL-1
Plate Location:
h8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
89 mg/mL; 183.9 mM
Water Max Solubility:
14 mg/mL; 28.9 mM
Ethanol Max Solubility:
12 mg/mL; 24.8 mM
