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RGX-202
Cat. No.:
0225LY-0846
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
RGX-202 is a structural analog of creatine that modulates energy expenditure in skeletal muscle by depleting cellular ATP, phosphocreatine, and creatine, which subsequently triggers AMPK and activates the PPARγ coactivator 1α (PGC-1α).
Synonym:
β-GPA; 3-Guanidinopropionic Acid; 353-09-3; 3-Guanidinopropionic acid; Beta-Guanidinopropionic acid; Guanidinopropionic acid; 3-Guanidinopropanoate; Ompenaclid; 3-carbamimidamidopropanoic acid; Beta-GPA; 3-(diaminomethylideneamino)propanoic acid; MFCD00045939; Beta-Guanadinopropionate; 3-guanidinopropanoicacid; b-Alanine, N-(aminoiminomethyl)-; PNU-10483; 3-Guanidino-propionic acid; N-(Aminomethyl)-beta-alanine
CAS No.:
353-09-3
Compound CID:
67701
Formula:
C4H9N3O2
Formula Weight:
131.13
Specification
Relative Density:
1.46 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
RGX-202 can be used in oncology research to explore the inhibition of creatine transport in colorectal cancer cells.
Library Information
Target:
AMPK; PPAR
Receptor:
AMPK; PPARγ
Pathways:
Metabolism; DNA damage/DNA repair; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-11
Plate Location:
h5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM Water
Water Max Solubility:
50 mg/mL; 381.3 mM
