Smoothened Agonist (SAG) HCl

Cat. No.: OB0225WX-2705

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Smoothened Agonist (SAG) HCl functions as a cell-permeable Smo receptor activator, exhibiting an effective concentration (EC50) of 3 nM in Shh-LIGHT2 cellular models.

Synonym: SAG hydrochloride; 2095432-58-7; SAG HCl; SAG (hydrochloride); Smoothened Agonist Hydrochloride; 2095432-58-7 (HCl); Smoothened Agonist HCl; 3-chloro-N-((1r,4r)-4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide hydrochloride; 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide;hydrochloride; Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-, hydrochloride; rel-3-Chloro-N-((1r,4r)-4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide hydrochloride

CAS No.: 2095432-58-7

Compound CID: 121540649

Formula: C₂₈H₂₉Cl₂N₃OS

Formula Weight: 526.52

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Smoothened Agonist (SAG) HCl is utilized in developmental biology and stem cell research to investigate the direct activation of the Smoothened receptor and the subsequent stimulation of the Hedgehog signaling pathway.