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Propionic acid-d5
Cat. No.:
OB0626WX-394
Appearance:
Oil
Purity:
≥99% (deuterated forms, d1-d5)
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
Propionic acid-d5 is a stable isotope-labeled internal standard developed for the high-sensitivity mass spectrometry-based quantification (GC-MS or LC-MS) of native propionic acid. The corresponding un-labeled analyte is a critical short-chain fatty acid generated principally through the anaerobic bacterial fermentation of dietary fibers within the colon and naturally found across diverse fermented dairy matrices like yogurt; it operates as an endogenous agonist of free fatty acid receptors FFAR2/GPR43 and FFAR3/GPR41, suppressing forskolin-stimulated cAMP accumulation in CHO-K1 lines with EC50 values of 14 and 6.2 µM, respectively, while inducing polymorphonuclear neutrophil chemotaxis at 1 mM.
Labeling:
Stable isotope-labeled
Synonyms:
Propanoic-d5 acid; Propanoic Acid-d5; Propionate-d5; FA 3:0-d5; Propionic-d5 acid; 2,2,3,3,3-pentadeuteriopropanoic acid; d5-propanoic acid; 60153-92-6
CAS No.:
60153-92-6
Compound CID:
59152704
Formula:
C3HD5O2
Formula Weight:
79.1
Specification
Solubility in Other Solvents:
Soluble in methanol and water.
Storage:
Storage at -20°C.
Applications:
Propionic acid-d5 operates as a heavily deuterated short-chain fatty acid reference standard for high-precision quantification, assisting in recovery determination and eliminating endogenous background variables during volatile fatty acid metabolic analysis.