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Pravastatin sodium
Cat. No.:
OB0225WX-2546
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Pravastatin sodium is an HMG-CoA reductase antagonist that suppresses the enzymatic synthesis of sterols with an IC50 of 5.6 μM.
Synonym:
CS-514 Sodium; 81131-70-6; Mevalotin; Pravachol; Selektine; Elisor; Pravaselect; Lipostat; Pravastatin Sodium Salt; Eptastatin sodium; CS-514; Dehypotin protect; Pravastatin (sodium); Lipemol; Pravacol; Pravasin; MFCD00887601; Pravastatin (sodium) (Standard); Sodium;(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate; Aplactin; Lipidal; Liprevil; Pralidon; Pravasine; Sanaprav; Selipran; Vasen; Epastatin sodium; (3R,5R)-3,5-Dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid, sodium salt; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, sodium salt (1:1), (betaR,deltaR,1S,2S,6S,8S,8aR)-; Sodium (+)-(betaR,deltaR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-hexahydro-beta,delta,6,8-tetrahydroxy-2-methyl-1-naphthaleneheptanoate, 8-((2S)-2-methylbutyrate); Sodium (3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-
CAS No.:
81131-70-6
Compound CID:
16759173
Formula:
C23H35O7·Na
Formula Weight:
446.51
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Pravastatin sodium is used in lipid metabolism research as a hydrophilic HMG-CoA reductase inhibitor to study the reduction of cholesterol biosynthesis and the prevention of atherosclerotic cardiovascular events.
Library Information
Target:
HMG-CoA reductase
Receptor:
HMG-CoA reductase
Pathways:
Metabolism
Plate Number:
L6700-05
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
89 mg/mL; 199.32 mM
Water Max Solubility:
89 mg/mL; 199.32 mM
ALogP:
0.682
HBA_Count:
2
HBD_Count:
3
Rotatable Bond:
11





