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PF-5006739
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Cat. No.:
OB0425LY-087
Synonyms:
1293395-67-1; PF 5006739; 2-Pyrimidinamine, 4-[4-(4-fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-; 4-[4-(4-Fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-2-pyrimidinamine
Size:
5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg
CAS No.:
1293395-67-1
Compound CID:
51353555
Specification
Description:
PF-5006739 is a potent and selective CK1δ/ε inhibitor.
Formula Weight:
419.45
Applications:
PF-5006739 can be used to improve glucose tolerance in diet-induced obesity (DIO) and genetic obesity (ob/ob) mouse models.
Storage:
Storage at 4°C.
Formula:
C22H22FN7O
Appearance:
Solid
Purity:
99.56% determined by HPLC.
Solubility:
DMSO
Pathway:
Cell cycle/DNA damage; Stem cell/Wnt
Identity:
Confirmed by NMR and MS.
Target:
Casein kinase
Library Information
Solubility:
DMSO