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Ouabain-d3
Cat. No.:
OB0626WX-372
Appearance:
Solid
Purity:
≥99% (deuterated forms, d1-d3)
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Ouabain-d3 is a stable isotope-labeled internal standard designed for the definitive mass spectrometry-based quantification (GC-MS or LC-MS) of native ouabain. The corresponding unlabeled analyte is a classic cardenolide cardiac glycoside isolated from Strophanthus gratus that targets and inhibits the Na+/K+-ATPase pump isoforms alpha1beta1 and alpha2beta1 alongside the human-ether-a-go-go (hERG/Kv11.1) potassium channel with highly precise IC50 values of 97, 90, and 15.2 nM, respectively.
Labeling:
Stable isotope-labeled
Synonyms:
4-((1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one-3,5,5-d3; g-Strophanthin-d3
Formula:
C29H41D3O12
Formula Weight:
587.7
Specification
Source:
Synthetic
Storage:
Storage at -20°C.
Applications:
Ouabain-d3 functions as a stable isotope-labeled cardiotonic steroid tracking reference for liquid chromatography-mass spectrometry workflows, assisting in recovery determination and eliminating endogenous baseline overlap during target transport kinetics assays.