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Mandimycin
Cat. No.:
OB0626WX-148
Appearance:
Solid
Purity:
≥90%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Mandimycin is a polyketide-derived polyene macrolide antibiotic discovered in Streptomyces netropsis that exhibits profound antifungal potency, demonstrating minimum inhibitory concentrations (MICs) ranging from 0.125 to 2 µg/ml against several prominent multidrug-resistant fungal pathogens including Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus, and Candida glabrata.
Synonyms:
(1S,3R,4R,7R,11R,15S,16S,17R,18S,19E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,4,7,11,37-hexahydroxy-17-(((2R,4R,5R,6S)-4-hydroxy-5-(((2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-15,16,18-trimethyl-9,13-dioxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,23,25,27,29,31-hexaene-36-carboxylic acid
Formula:
C60H95NO23
Formula Weight:
1198.4
Specification
Source:
Streptomyces netropsis
Solubility in DMSO:
0.1-1 mg/mL
Storage:
Storage at -20°C.
Applications:
Mandimycin serves as a natural product reference compound for secondary metabolite characterization, chromatographic method development, and investigation of structurally diverse microbial-derived compounds.