Products
Online Inquiry
Lithocholic-2,2,4,4-d4 acid 3-sulfate, sodium salt
Cat. No.:
OB0626WX-111
Appearance:
Solid
Purity:
≥99% (deuterated forms, d1–d4)
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
Lithocholic-2,2,4,4-d4 acid 3-sulfate is a stable isotope-labeled internal standard designed for the definitive quantification of endogenous lithocholic acid 3-sulfate via GC-MS or LC-MS platforms. The corresponding native molecule is a major water-soluble metabolite of the secondary bile acid lithocholic acid that stands as the predominant biliary form within the bile duct, demonstrates a distinct capacity to complex with calcium ions in vitro, and displays elevated biliary secretion dynamics in streptozotocin-induced diabetic rat models.
Labeling:
Stable isotope-labeled
Synonyms:
(3α,5β)-3-(sulfooxy)-cholan-24-oic-2,2,4,4-d4 acid, disodium salt; LCA-d4 3-sulfate; Lithocholate-d4 3-sulfate
Formula:
C24H34D4O6S • 2Na
Formula Weight:
504.6
Specification
Solubility in DMSO:
1-10 mg/mL
Storage:
Storage at -20°C.
Applications:
Lithocholic-2,2,4,4-d4 acid 3-sulfate, sodium salt serves as a stable isotope-labeled sulfated bile acid standard for quantitative bile acid analysis and lipidomic profiling. It supports isotope dilution workflows, mass spectrometry calibration, and characterization of sulfated bile acid metabolites.