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Lipoxin A4-d5
Cat. No.:
OB0626WX-2805
Appearance:
Liquid
Purity:
≥99% (deuterated forms, d1-d5)
Identity:
Confirmed by TLC and HPLC.
Size:
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Product Overview
Description:
Lipoxin A4-d5 is an isotopically enriched internal standard containing five deuterium atoms, tailored for the robust quantitative profiling of native lipoxin A4 via chromatography-mass spectrometry. The native analyte is a trihydroxy, conjugated tetraene-containing oxylipin biosynthesized through leukocyte-mediated lipoxygenase cross-talk, acting as a potent regulatory mediator that coordinates neutrophil activation, chemotaxis, and cellular adhesion cascades.
Labeling:
Stable isotope-labeled
Synonyms:
5S,6R,15S-trihydroxyicosa-7E,9E,11Z,13E-tetraenoic-19,19,20,20,20-d5 acid; LXA4-d5; 1622429-53-1; (5S,6R,7E,9E,11Z,13E,15S)-19,19,20,20,20-pentadeuterio-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid; 5S,6R,15S-trihydroxyicosa-7E,9E,11Z,13E-tetraenoic-19,19,20,20,20-d5acid; LXA4-[19,19,20,20,20-d5]; 5(S),6(R)-Lipoxin A4-d5; 5S,6R-LipoxinA4-d5; 5(S),6(R),15(S)-TriHETE-d5; 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic-19,19,20,20,20-d5 acid
CAS No.:
1622429-53-1
Compound CID:
139291900
Formula:
C20H27D5O5
Formula Weight:
357.5
Specification
λmax:
302 nm
Solubility in Ethanol:
50 mg/mL
Solubility in DMF:
50 mg/mL
Solubility in Other Solvents:
PBS: 1 mg/mL
Storage:
Storage at -80°C.
Applications:
Lipoxin A4-d5 serves as an isotopically labeled reference standard for specialized lipid mediator analysis. It supports quantitative lipidomics, isotope dilution workflows, LC-MS/MS method development, and analytical characterization of lipoxin-related metabolites.