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Lalistat 2
Cat. No.:
OB0225WX-1871
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Lalistat 2 acts as a selective inhibitor of lysosomal acid lipase with an IC50 of 152 nM, demonstrating a lack of inhibitory effect on bovine milk or human pancreatic lipases.
Synonym:
1234569-09-5; 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate; 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-ylpiperidine-1-carboxylate; 1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester
CAS No.:
1234569-09-5
Compound CID:
46867138
Formula:
C13H20N4O2S
Formula Weight:
296.39
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Lalistat 2 is utilized in metabolic and lysosomal research as a potent and selective inhibitor of lysosomal acid lipase (LAL) to investigate the biochemical mechanisms of cholesterol ester and triglyceride hydrolysis.
Library Information
Target:
Lipase
Receptor:
Lysosomal acid Lipase
Pathways:
Metabolism
Plate Number:
AOCL-25
Plate Location:
a2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 168.7 mM
