GW3965 HCl

Cat. No.: OB0225WX-2503

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

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Product Overview

Description: GW3965 HCl is a potent and selective agonist of the liver X receptors hLXR-alpha and hLXR-beta, exhibiting EC50 values of 190 nM and 30 nM in biochemical assays, respectively.

Synonym: 405911-17-3; GW3965 hydrochloride; 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride; GW3965 (hydrochloride); MFCD08276920; 2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride; 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid;hydrochloride; 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic acid hydrochloride; 3-[3-[N-(2-Chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride; GW3965 HCl; 2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy)-phenyl)acetic acid hydrochloride salt; 2-(3-{3-[[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy}-phenyl)acetic acid hydrochloride salt; GW-3965 hydrochloride; (3-{3-[{[2-Chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino]propoxy}phenyl)acetic acid--hydrogen chloride (1/1); (3-{3[(2-chloro-3-trifluoromethyl-benzyl)-diphenylethyl-amino]-propoxy}-phenyl)-acetic acid hydrochloride salt; 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneaceticacidhydrochloride; 3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride

CAS No.: 405911-17-3

Compound CID: 16078973

Formula: C₃₃H₃₁ClF₃NO₃·HCl

Formula Weight: 618.51

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: GW3965 HCl is employed in metabolic research as a potent and selective LXR agonist to investigate the regulation of cholesterol efflux, lipid metabolism, and inflammatory gene expression.