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GCS-12
Cat. No.:
OB0626WX-179
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
GCS-12 is a highly potent glycolipid ligand engineered as a derivative of alpha-galactosylceramide (alpha-GalCer) incorporating a structural sulfonamide modification at carbon 12 of the ceramide N-acyl chain, functioning as a selective CD1d receptor agonist and an intense natural killer T (NKT) cell activator.
Synonyms:
N-((2S,3S,4R)-3,4-dihydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadecan-2-yl)-12-(dodecylsulfonamido)dodecanamide
Formula:
C48H96N2O11S
Formula Weight:
909.4
Specification
Solubility in Other Solvents:
Chloroform: 0.1-1 mg/mL; Methanol: 0.1-1 mg/mL
Storage:
Storage at -20°C.
Applications:
GCS-12 serves as a defined lipid reference compound for investigating lipid formulation properties, membrane phase behavior, and structural characterization of synthetic lipid systems.