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Estrone 3-sulfate, sodium salt
Cat. No.:
OB0626WX-577
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
Estrone 3-sulfate is a major endogenous circulating steroid conjugate that functions as a highly stable metabolic reservoir, readily undergoing in vivo enzymatic conversion into free estrone. Beyond its role in steroid hormone homeostasis, this sulfated estrogen acts as a highly selective inhibitor of organic anion transporting polypeptide 1B1 (OATP1B1) kinetics over OATP1B3.
Synonyms:
3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, monosodium salt; Estrone sulfate; Estrone sulfate sodium; Sodium estrone sulfate; Conestoral; Hyhorin; Morestin; Par Estro; Sodium estrone 3-sulfate; Estrone sulfate sodium salt; Sodium estrone sulphate; Estrone-3-sulfate sodium salt; Sodium estrone-3-sulfate; Oestrone-3-sulphate sodium salt; Estrogenic substances (conjugated); NSC 18313; Estrone 3-sulfate sodium salt; Estrone sulfate (sodium); 438-67-5
CAS No.:
438-67-5
Compound CID:
23667301
Formula:
C18H21O5S • Na
Formula Weight:
372.4
Specification
Solubility in DMSO:
30 mg/mL
Solubility in Ethanol:
2 mg/mL
Solubility in DMF:
30 mg/mL
Solubility in Other Solvents:
DMSO:PBS mixture: 0.5 mg/mL
Storage:
Storage at -20°C.
Applications:
Estrone 3-sulfate, sodium salt serves as an analytically stable, sulfated estrogen metabolite baseline tool for calibrating steroidomic separation workflows, investigating sulfatase-mediated structural interconversions, and profiling localized ligand-protein transport mechanics within model cellular matrices.