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Emindole SB
Cat. No.:
OB0626WX-57
Appearance:
Solid
Purity:
≥95%
Size:
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Product Overview
Description:
Emindole SB is an indoloditerpene metabolite naturally identified in Diheterospora cejpii that exhibits multi-targeted pharmacological profiles, acting as a competitive cannabinoid 1 (CB1) and CB2 receptor antagonist with Ki values of 7.05 and 2.24 µM, respectively, while simultaneously functioning as a dual-enzyme inhibitor that suppresses protein tyrosine phosphatase 1B (PTP1B) and T cell protein tyrosine phosphatase (TCPTP) with IC50 values of 1.6 and 2.4 µM, respectively.
Synonyms:
1,2,3S,4S,4aR,5,6,6aS,7,12,12bS,12cS-dodecahydro-4,12b,12c-trimethyl-4-(4-methyl-3-penten-1-yl)-benz[6,7]indeno[1,2-b]indol-3-ol; 112900-04-6
CAS No.:
112900-04-6
Compound CID:
CID 9887568 (Emindole Sb)
Formula:
C28H39NO
Formula Weight:
405.6
Specification
Source:
Aspergillus sp.
Storage:
Storage at -20°C.
Applications:
Emindole SB serves as an indole diterpenoid reference compound for analytical characterization, natural product profiling, and investigation of lipophilic small-molecule properties. It supports metabolite identification workflows, chromatographic method development, and comparative analysis of fungal-derived compounds.