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Desogestrel-13C2-d2
Cat. No.:
OB0626WX-706
Appearance:
Solid
Purity:
≥99% (deuterated forms, d1-d2)
Identity:
Confirmed by NMR and TLC.
Size:
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Product Overview
Description:
Desogestrel-13C2-d2 is a stable isotope internal standard incorporating a dual carbon-13 and dual deuterium label configuration, specifically engineered for the absolute, high-precision quantification of desogestrel profiles via advanced GC-MS or LC-MS assays. The corresponding unlabeled target analyte is a potent synthetic progestogen that blocks ovulation and prevents overall fertilization thresholds in rabbit and murine models, while demonstrating a dose-dependent, ex vivo inhibition of rhodamine 123 efflux within human lymphocytes and CD8+ T cells—a direct functional indicator of P-glycoprotein transporter modulation.
Labeling:
Stable isotope-labeled
Synonyms:
(8S,9S,10R,13S,14S,17R)-13-ethyl-17-(ethynyl-13C2)-11-methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-16,16-d2-17-ol
Formula:
C2013C2H28D2O
Formula Weight:
314.5
Specification
Solubility in Other Solvents:
Slightly soluble in chloroform and methanol.
Storage:
Storage at -20°C.
Applications:
Desogestrel-13C2-d2 functions as a dual stable isotope-labeled progestin internal reference engineered for high-resolution mass spectrometry pipelines, providing a distinct, non-overlapping mass shift to secure quantitative accuracy and correct for extraction recovery variations.